I'm vaguely aware of Alphas and I think I just had a dream regarding the show. Nothing too concrete, just concepts and ideas that stemmed from catching a few too many promos for it and not taking the time to actually get into it.
I think they're doing it wrong, of course.
In my dream, the framing sequence is the introduction of the "mutated" folk through an interview with the POV character-- a police detective?-- and the history of the program being given like that. Characters include a telepath/an invulnerable geek kind of fellow/super speed loser. Their training would be shown, including a scene with dozens of zombies linked together and they have to get to the other side... the geek catapults himslef to the other side... then there's a room of zombies (I don't know how zombies came into it) they have to get from one side to the other of, and the person who is directing the team, who has watched them suffer, who has been in their heads, she decides to help, goes around distracting zombies and twatting them in the head... and then the POV character would say that's all well and good but why has HE been called here.
Some mutated folk were trained differently. They were let out into the world, adopted, and the world shaped them. The detective (hyper-intuitive), the olympic swimmer (hyper-metabolism), the fireman (fearless), etc. The core group of characters, really.
The detective is one of them. He's shocked, but things make sense to him (thanks to his deductive reasoning powers). What he also wants to know is why the scientist in charge of the program is so battered and bruised...
Six mutated subjects escaped recently. Horrific mutations with names taken from nursery rhymes... The Spider ("...Itsy Bitsy..."), The Wolf, The Headsman, Hansel & Gretel... and they're going to kill everyone because they hate humanity for experimenting on them. The Spider is the ring leader of this group. He induced a change in the subjects, made them shed their skin and break free from their bonds-- nano bonds?-- and unleash hell. They destroyed the labs, killed dozens of the more passive subjects and the scientists, and then left. All apart from The Spider. The lead scientist arrived in the lab and found it in chaos. The Spider was waiting. The scientist picked up a discarded weapon, hides in a toilet cubicle, while The Spider monologues. The bullets ricochet off of The Spider, who mocks the scientist as he tears the door off the toilet. He then proceeds to take a DNA sample of the scientist and then one of himself. He swaps them and injects a into b and b into a.
The subjects are all the scientist's children-- he experimented on himself decades ago and his power was his super-power giving biological make-up. The Spider contaminates his body with his own DNA, twisting any potential super-children into copies of himself-- genetic clones?-- so no more can be made. And with the scientist's DNA in him... The Spider might be able to breed super-powered creatures (imagine a story where a pregnant woman is found in a hotel, her bloated, stretched belly bursting with dozens of mutated foetuses...).
So. The detective needs to bring these monsters in. He needs to take The Spider alive so they can undo the genetic damage done to the scientist so the program can continue. He intuits that the DNA might be changing the scientist but chooses to trust him, and then he assembles his team!
So that would be the story. Dollhouse-meets-Alphas?
I could write that.